C A E S A

Computer Assisted Estimation of Synthetic Accessibility

Intermediate steps for	Used databases:	Aldrich Database, Maybridge Database
vasotec.mol	Source file:	/var/www/html/caesa_work/preprocess/top_drugs/top_drugs.sd

Score	Group Number	Database Reference	Source Database
43	4	11058	Aldrich Database

Explanations:

Starting material defined relative
STEREO: Mapped 0 Inverted 0 Undefined 2
Ease of intercovertibility: Reasonable (6)
The following synthetic steps were used to generate this starting material
... Oxygen Generalisation (Carboxy)
The following complexity features are fully contained within
this starting materials and are not considered to contribute
to the synthetic complexity of the target structure.
... 5 Membered ring
... Cyclic appendage with heteroatom alpha
... Secondary Stereocentre
... Cyclic Stereocentre
... Isolated Stereocentre

Retrosynthetic steps:

... Amide Formation 1

... Carboxy Oxidation

C A E S A

Intermediate steps for

vasotec.mol