C A E S A

Computer Assisted Estimation of Synthetic Accessibility

Intermediate steps for	Used databases:	Aldrich Database, Maybridge Database
augmentin.mol	Source file:	/var/www/html/caesa_work/preprocess/top_drugs/top_drugs.sd

Score	Group Number	Database Reference	Source Database
21	0	7244	Aldrich Database

Explanations:

Starting material defined relative
Number of incorrectly mapped olefins : 1
Ease of intercovertibility: Hard (12)
The following synthetic steps were used to generate this starting material
... Keto/Enol
... Reduction of Carboxylic Acid
The following complexity features are fully contained within
this starting materials and are not considered to contribute
to the synthetic complexity of the target structure.
... Formation of an Acylic Carbon-Carbon bond may cause a problem
... 5 Membered ring
... Olefin

Retrosynthetic steps:

... Ether Formation (Halogen)

... Ene

C A E S A

Intermediate steps for

augmentin.mol