Hi, Let me introduce myself. My name is Dan (Danni) Harris and I have just joined the passionate SimBioSys Team. I have over the course of 20+ years been involved with implementing and developing unique approaches in both structure-based and indirect design, including software development to facilitate those approaches. This includes facets of lead discovery, optimization, DMPK, predictive toxicology, bio- and chemoinformatics, investigation of protein-ligand and protein-protein interactions, and quantum chemical investigations of biochemical reaction pathways. I continue to work on several of these facets as I join the SimBiosys team to deliver (sell) and support new software lead discovery and optimization solutions on both ‘conventional’ workstations and new Cell Broadband architecture.
Over the past 20 years I’ve had the pleasure of working with many of the primary software applications in the industry and have provided feedback and guidance to the numerous development teams and vendors regarding how to improve the applications. It felt like a good time with getting directly involved with the process so joining SimBioSys is an ideal opportunity to apply my insights and help the development team here deliver an optimal product (personally I think it’s damn good as it is!!!).
Having used many other vendors software I was very happy to join a company focused on cutting-edge innovations and delivery of products driven both by customers requests as well as their own insights and expertise. Certainly the opportunity to work with the Technical Lead of SimBioSys, Zsolt Zsoldos, is exciting. It was his vision that will bring eHiTS lightning (eHiTS on the Cell) to market ahead of the innovation curve relative to other companies. Zsolt and I have already had many opinionated discussions challenging each others experience and expectations and note that we are like-minded in delivering the best solutions to market. I will be blogging in coming days about some of the new technical developments as well as feedback to Zsolt’s vibrant presentation at the 2008 ACS meeting. I hope to have some lively exchanges about the challenges of lead-discovery. I think one thing we will agree upon is that ‘having the best tools to the task’ (see figure— that’s me on the tractor) is essential to a fruitful harvest (pun intended).
The SimBioSys toolset focused on a comprehensive Fragment Based approach to ‘screening’ and synthesis is (like the picture above) is unconventional, novel, fast and accurate. Stay tuned to new developments coming this month! DLH.